I upgraded to WordPress 2.5 yesterday. Everything seems to have gone well, except I forgot to re-generate my .htaccess file, which caused all the permalinks on the site to fail, as well as the RSS feed to fail.
I've also stopped showing Google ads on my site. I did this because somehow ads for abortion clinics kept popping up. Google doesn't give you that much control over what kind of advertisements are shown, and since I'm not at all comfortable with these kinds of ads, I've pulled them for now. For those "in the know", this has nothing to do with recent events :)